Lariam (Mefloquine) – What You Need to Know Before Your Trip

If you’re planning travel to a malaria‑risk area, chances are you’ve heard the name Lariam. It’s the brand name for mefloquine, an antimalarial pill taken before, during, and after exposure to infected mosquitoes. Below we break down why it matters, how to use it right, and what to watch out for.

How Lariam Works and When to Take It

Lariam kills the malaria parasite while it’s still in your bloodstream. Doctors usually prescribe a single 250 mg dose once a week. You start taking it at least one week before you enter the endemic zone, keep up the weekly schedule throughout your stay, and continue for four weeks after you leave.

The timing is key because mefloquine builds up in your system slowly. Skipping a dose can lower protection and raise the risk of infection. If you miss a pill, take it as soon as you remember unless it’s less than 24 hours before the next scheduled dose – then just skip the missed one.

Safety Tips & Common Side Effects

Most people tolerate Lariam well, but about 10‑15% notice side effects. The most common are stomach upset, headache, and dizziness. These usually fade after a few days as your body adjusts.

A smaller group experiences mood changes like anxiety, vivid dreams, or trouble sleeping. If you feel severe depression, hallucinations, or thoughts of harming yourself, stop the drug immediately and seek medical help.

Before you start, tell your doctor about any history of mental health issues, seizures, or heart problems. Lariam can interact with some antidepressants and anti‑arrhythmic meds, so a quick medication check is worth it.

Pregnant women should avoid Lariam unless there’s no safer alternative – the drug crosses the placenta and could affect the baby. Breastfeeding moms face similar concerns.

When buying Lariam online, stick to reputable pharmacies that require a prescription. Look for verification symbols or reviews that confirm they follow local pharmacy laws.

If you’re unsure whether Lariam is right for your trip, talk to a travel clinic. They can compare it with other options like doxycycline or atovaquone‑proguanil and pick the best fit based on destination, length of stay, and personal health.

Bottom line: Lariam is a proven tool against malaria when used correctly. Keep your dosing schedule tight, watch for side effects, and always get it from a trusted source. With these steps, you’ll reduce the chance of catching malaria and enjoy a safer journey.